COLOR-VISION LOSS IN WORKERS EXPOSED TO ELEMENTAL MERCURY-VAPOR

Citation
A. Cavalleri et al., COLOR-VISION LOSS IN WORKERS EXPOSED TO ELEMENTAL MERCURY-VAPOR, Toxicology letters, 77(1-3), 1995, pp. 351-356
Citations number
25
Categorie Soggetti
Toxicology
Journal title
ISSN journal
03784274
Volume
77
Issue
1-3
Year of publication
1995
Pages
351 - 356
Database
ISI
SICI code
0378-4274(1995)77:1-3<351:CLIWET>2.0.ZU;2-3
Abstract
We evaluated colour vision in 33 workers exposed to elemental mercury (Hg) vapour and in 33 referents matched for sex, age, alcohol consumpt ion and cigarette smoking. The results were expressed as colour confus ion index (CCI). In the workers urinary excretion of Hg (HgU) ranged f rom 28 to 287 mu g/g creatinine. Subclinical colour vision loss, mainl y in the blue-yellow range, was observed in the workers. This effect w as related to exposure, as indicated by the correlation between HgU an d CCI (r = 0.488, P < 0.01). In the workers whose HgU exceeded 50 mu g /g creatinine, mean CCI was significantly increased compared to the ma tched referents. The results suggest that exposure to elemental Hg ind ucing HgU values exceeding 50 mu g/g creatinine can induce a dose-rela ted colour vision loss.