ASSOCIATION BETWEEN HEPATITIS-C VIRUS SEROREACTIVITY AND HIV-INFECTION IN NON-INTRAVENOUS DRUG ABUSING PROSTITUTES

Two hundred and ninety-four non-transfused prostitutes from Spain, who denied intravenous drug abuse, were tested for hepatitis C virus (HCV ) antibodies. Seventeen (5.78%) of them were seropositive. Both in uni variate and correspondence analyses, serological results for hepatitis C were associated with the HIV-1 serostatus (p < 0.001), number of se x partners (p < 0.05) and a history of genital ulcers (p < 0.05). In l ogistic regression analysis, hepatitis C seropositivity was associated only with HIV-1 infection (adjusted odds ratio = 13.6; 95 % confidenc e interval = 3.3-55.2). These results show that hepatitis C seropositi vity is associated with HIV-1 infection in female nonintravenous drug abusing prostitutes. These findings are also consistent with the hypot hesis that HCV can be sexually transmitted with low efficiency.