CEREBRAL PROTON MAGNETIC-RESONANCE SPECTROSCOPY IN RETT-SYNDROME

Authors
HANEFELD F CHRISTEN HJ HOLZBACH U KRUSE B FRAHM J HANICKE W
Citation
F. Hanefeld et al., CEREBRAL PROTON MAGNETIC-RESONANCE SPECTROSCOPY IN RETT-SYNDROME, Neuropediatrics, 26(2), 1995, pp. 126-127
Citations number
12
Categorie Soggetti
Pediatrics,Neurosciences
Journal title
Neuropediatrics → ACNP
ISSN journal
0174304X
Volume
26
Issue
2
Year of publication
1995
Pages
126 - 127
Database
ISI
SICI code
0174-304X(1995)26:2<126:CPMSIR>2.0.ZU;2-P
Abstract
Combined MRI/MRS studies were performed in 9 girls with Rett syndrome of different ages. NAA, as marker of neuronal tissue, was found to dec rease with increasing age. There was no evidence for a defective energ y metabolism. The data point towards a probably secondary degenerative process in the pathogenesis of Rett syndrome.