Ischemia of the upper extremity is unusual, particularly in patients w
ithout trauma or iatrogenic injury to the vessels of the arm. Some aut
hors have suggested that ischemia of the upper extremity is one sixth
as common as that in the leg. Management of patients with vascular tra
uma or iatrogenic injury is usually straightforward, with direct repai
r or vein grafting of the injured vessel. Patients with ischemia from
vascular disease, however, present a different set of management probl
ems. These individuals often suffer from systemic medical problems tha
t lead to their vascular disease, which is often very severe and accel
erated because of the underlying cause. This article discusses the app
roach to these patients and options for management.