A. Roignant et al., MONO-DIALKYLATION AND N-1,N-7-DIALKYLATION OF 1,4,7,10-TETRAAZACYCLODODECANE VIA SILICON PROTECTION, Journal of the Chemical Society, Chemical Communications, (12), 1995, pp. 1233-1234
The protection of 1,4,7,10-tetraazacyclododecane by a methylsilyl grou
p leads selectively to N-mono- and N-1,N-7-symmetrically or dissymmetr
ically alkylated compounds.