AIDS-RELATED LYMPHOMA - RADIOLOGIC FEATURES IN PEDIATRIC-PATIENTS

PURPOSE: To determine the clinical, pathologic, and radiologic feature s in pediatric patients with acquired immunodeficiency syndrome (AIDS) related lymphoma and to compare these features with those in adult pat ients with AIDS-related lymphoma. MATERIALS AND METHODS: Clinical and radiologic findings were retrospectively reviewed in nine children (ag ed 1-15 years) with AIDS-related lymphoma. All patients had neoplastic changes that were not consistent with hyperplastic lymphoid tissue. T he children underwent ultrasonography, computed tomography, magnetic r esonance imaging, and plain radiography. RESULTS: Sites of involvement by malignant non-Hodgkin lymphoma at diagnosis were the liver (n = 7) , spleen (n = 5), kidney (n = 4), central nervous system (n = 2), and testis and bone (n = 1). Symptoms included seizures, respiratory distr ess, testicular swelling, and increased abdominal girth. CONCLUSION Ch ildren with AIDS-related lymphoma have symptoms distinct from those fo und in adults, but clinical, radiologic, and pathologic findings show that almost any anatomic site in these children can be involved.