OXYSPORIDINONE - A NOVEL, ANTIFUNGAL N-METHYL-4-HYDROXY-2-PYRIDONE FROM FUSARIUM-OXYSPORUM

Authors
BREINHOLT J LUDVIGSEN S RASSING BR ROSENDAHL CN NIELSEN SE OLSEN CE
Citation
J. Breinholt et al., OXYSPORIDINONE - A NOVEL, ANTIFUNGAL N-METHYL-4-HYDROXY-2-PYRIDONE FROM FUSARIUM-OXYSPORUM, Journal of natural products, 60(1), 1997, pp. 33-35
Citations number
19
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy","Chemistry Medicinal
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
60
Issue
1
Year of publication
1997
Pages
33 - 35
Database
ISI
SICI code
0163-3864(1997)60:1<33:O-ANAN>2.0.ZU;2-9
Abstract
Oxysporidinone (1), a novel 3,5-disubstituted N-methyl-4-hydroxy-2-pyr idone, was isolated from fermentations of Fusarium oxysporum (CBS 330. 95) by counter-current chromatography. The structure was determined by spectroscopic methods including NMR, MS, IR, and UV analysis. Oxyspor idinone exhibited growth inhibitory activity against several common pl ant pathogenic fungi.