Ea. Zhavrid et al., POSSIBILITY OF INDIVIDUAL RADIOSENSITIVIT Y MODIFICATION OF MALIGNANT-TUMORS BY ARTIFICIAL HYPERGLYCEMIA, Eksperimental'naa onkologia, 16(4-6), 1994, pp. 423-429
The growth dynamics, the degree of morphologic changes ire two rat tum
or lines differing in PM-sensitivity, were studied under various doses
of irradiation combined with induced hyperglycemia, in early and late
stages of tumor disease. A direct relationship between the extent of
PH reduction under induced hyperglycemia and radiotherapy effect was a
scertained both in experiment and clinical treatment, We propose to us
e this parameter for individual prognosis of tumor sensitivity to the
radiomodifying effect of induced hyperglycemia.