Np. Buryakov et al., ENDOGENOUS SYNTHESIS OF N-NITROSODIMETHYL AMINE IN THE ALIMENTARY CANAL OF BROILERS WHEN USING POTASSIUM NITRITE CONTAINING FOODS, Eksperimental'naa onkologia, 16(4-6), 1994, pp. 469-471
The possibility of synthesis of carcinogenic volatile N-nitrosamines (
NA) in the alimentary canal content of broilers when adding potassium
nitrite to their foods and the effect of adding sodium ascorbate (a fo
od substitute of vitamin C) on the concentration of the formed N-nitro
sodimethylamine (NDMA) were studied, In 2 experiments with 50 (exp.1)
and 100 (exp.2) broilers fed with combined foods with potassium nitrit
e and sodium ascorbate up to the age of 7 weeks, the NA content for ea
ch experimental and control group was measured. A slight increase in N
DMA content was detected in the control, and 10-fold increase - in the
experiment (up to 3 ng/g). NDMA content was significantly lower when
30-50 mg of sodium ascorbate per kg of food were added, The studies we
re performed by means of the <<Tsvet>> gas chromatographer with therma
l energy analyzer TEA-502A (USA) used as a detector, with preliminary
vacuum distillation, methylene chloride extraction, using N-nitrosodip
ropylamine as an internal standard.