ENDOGENOUS SYNTHESIS OF N-NITROSODIMETHYL AMINE IN THE ALIMENTARY CANAL OF BROILERS WHEN USING POTASSIUM NITRITE CONTAINING FOODS

Citation
Np. Buryakov et al., ENDOGENOUS SYNTHESIS OF N-NITROSODIMETHYL AMINE IN THE ALIMENTARY CANAL OF BROILERS WHEN USING POTASSIUM NITRITE CONTAINING FOODS, Eksperimental'naa onkologia, 16(4-6), 1994, pp. 469-471
Citations number
4
Categorie Soggetti
Oncology
Journal title
ISSN journal
02043564
Volume
16
Issue
4-6
Year of publication
1994
Pages
469 - 471
Database
ISI
SICI code
0204-3564(1994)16:4-6<469:ESONAI>2.0.ZU;2-U
Abstract
The possibility of synthesis of carcinogenic volatile N-nitrosamines ( NA) in the alimentary canal content of broilers when adding potassium nitrite to their foods and the effect of adding sodium ascorbate (a fo od substitute of vitamin C) on the concentration of the formed N-nitro sodimethylamine (NDMA) were studied, In 2 experiments with 50 (exp.1) and 100 (exp.2) broilers fed with combined foods with potassium nitrit e and sodium ascorbate up to the age of 7 weeks, the NA content for ea ch experimental and control group was measured. A slight increase in N DMA content was detected in the control, and 10-fold increase - in the experiment (up to 3 ng/g). NDMA content was significantly lower when 30-50 mg of sodium ascorbate per kg of food were added, The studies we re performed by means of the <<Tsvet>> gas chromatographer with therma l energy analyzer TEA-502A (USA) used as a detector, with preliminary vacuum distillation, methylene chloride extraction, using N-nitrosodip ropylamine as an internal standard.