Acute diarrhoeal diseases continue to be a major health problem in cer
tain underprivileged populations in the United States, including nativ
e Americans living in reservations. To describe the features of patien
ts with diarrhoeal diseases requiring medical care, those attending th
e medical facilities of the Fort Apache Indian Reservation, Whiteriver
, Arizona, were studied during 1981-1985. Clinical and aetiological in
formation was obtained on 535 patients which constitute a 20% sample o
f those attending the outpatient clinic and all 386 patients who requi
red 550 hospitalizations. Rotavirus, enterotoxigenic Escherichia coli,
and Shigella were the most common aetiologic agents, a pattern simila
r to that seen in the developing countries. The clinical features of d
iarrhoeal illness and the frequent associated occurrence of acute resp
iratory symptoms, however, were remarkably similar, regardless of aeti
ology.