Since 1981, we have treated 46 adults aged 56 +/- 21 years, of whom 17
were diabetic, with intermittent peritoneal dialysis. Their mean time
on dialysis has been 21 months with an accumulated experience of 493
months/patient. The program included 2 dialyses per week, 25 exchanges
of 2 l per session and 30 min of dwell time. Arterial pressure contro
l has been satisfactory. Diabetic patients had lower levels of serum c
alcium, alkaline phosphatases and m-PTH. The incidence of peritonitis
has been 1 episode/14 months/patient and the causative agent has been
Staphylococcus aureus in 47% of episodes...Mean catheter duration has
been 15 months and 1 episode/34 months/patient of exit site infection
has been recorded and Staphylococcus aureus has been the causative age
nt in 83% of episodes. The risk of acquiring the first peritonitis was
12% at 3 months, 23% at 6 months and higher for non diabetic patients
. Actuarial survival of treated patients at 12 and 24 months was 89 an
d 67% respectively. No differences in survival were recorded between d
iabetic and non diabetic patients. Fifty two percent of patients that
dropped out continued on hemodialysis, 23% died, 11% abandoned treatme
nt, 8% continued on chronic ambulatory peritoneal dialysis and 6% rece
ived a kidney allograft. We conclude that intermittent peritoneal dial
ysis is a good alternative treatment of chronic renal failure, even in
diabetic patients.