Mycobacterium marinum is an atypical acid-fast organism that is rarely
associated with septic arthritis. Most often this is seen in patients
with monarticular synovitis of the hands or wrists, especially in ass
ociation with a history of periarticular trauma or exposure to marine
environments. From tissue obtained by aspiration or synovectomy, Mycob
acterium marinum can be identified by Ziehl-Nielson stain and has opti
mal growth in Lowenstein-Jenson medium. Therapy should consist of at l
east two antimycobacterial agents for a minimum 6 months. Surgical deb
ridement also may be beneficial. The clinician must have a high index
of suspicion that exposure to Mycobacterium marinum has occurred so ap
propriate stains and cultures can be obtained. Copyright (C) 1995 by W
.B. Saunders Company