Many signals measured from the nervous system exhibit apparently rando
m variability that is usually considered to be noise. The development
of chaos theory has revealed that such random appearing variability ma
y not, in fact, be random, but rather may be deterministic behavior th
at can reveal important information about the system's underlying mech
anisms. We present some new methods for distinguishing determinism fro
m randomness in experimental data, and we apply these methods to popul
ation neural responses recorded from hippocampal tissue slices.