NUCLEAR MIGRATION ADVANCES IN FUNGI

Nuclear migration encompasses three areas: separation of daughter nucl ei during mitosis, congress of parental nuclei before they fuse during fertilization, and positioning of nuclei in interphase cells. This re view deals primarily with interphase nuclear migration, which is cruci al for events as disparate as vertebrate embryonic development and gro wth of fungal mycelia. Mutants of Aspergillus nidulans, Neurospora cra ssa and Saccharomyces cerevisiae have been particularly informative, a nd a detailed molecular analysis of this process is now well under way .