Although magnetic resonance imaging has been proposed for the diagnosi
s of deep venous thrombosis (DVT), its role in diagnostic strategy rem
ains to be defined. We compared prospectively magnetic resonance angio
graphy (MRA) with two-dimensional time-of-flight with contrast venogra
phy (CV) and colour duplex sonography (CDS) in 25 patients with DVT of
the pelvis confirmed by CV. All patients were examined by CV (gold st
andard) and MRA and 17 by CDS. These studies were compared for DVT dia
gnosis in the pelvis and inferior vena cava and analysis of thrombotic
spread. MRA was positive in 25 patients whose DVT was diagnosed by CV
(100% sensitivity). MRA sensitivity and negative predictive value wer
e 100%, specificity 98.5% and positive predictive value 97.5% for the
diagnosis of thrombosis at each anatomic level. There were discrepanci
es between MRA and CV (2 false-positive results for 2 venous segments)
and between CDS and CV (2 false-positive and 3 false-negative results
). CV was uninterpretable for 8.8% of segments and CDS was often techn
ically limited to the pelvic level, whereas all venous segments explor
ed were analysable in MRA. MRA gave excellent results for positive dia
gnosis and DVT spread. MRA is a potentially valuable technique for ass
essing iliofemorocaval venous thrombosis.