The complete nucleotide sequence of Saccharomyces cerevisiae chromosom
e VI (270 kb) has revealed that it contains 129 predicted or known gen
es (300 bp or longer). Thirty-seven (28%) of which have been identifie
d previously. Among the 92 novel genes, 39 are highly homologous to pr
eviously identified genes. Local sequence motifs were compared to acti
ve ARS regions and inactive loci with perfect ARS core sequences to ex
amine the relationship between these motifs and ARS activity. Addition
al ARS sequences were predominantly observed in 3' flanking sequences
of active ARS loci.