SYNTHESIS OF PROTECTED NONPROTEINURIC ALP HA-AMINO-ACIDS AND OLIGOPEPTIDES FROM 2H-1,3-OXAZINES AND 2H-1,3-BENZOXAZINES VIA UGI REACTION

Authors
GROGER H HATAM M MARTENS J
Citation
H. Groger et al., SYNTHESIS OF PROTECTED NONPROTEINURIC ALP HA-AMINO-ACIDS AND OLIGOPEPTIDES FROM 2H-1,3-OXAZINES AND 2H-1,3-BENZOXAZINES VIA UGI REACTION, Tetrahedron, 51(26), 1995, pp. 7173-7180
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
26
Year of publication
1995
Pages
7173 - 7180
Database
ISI
SICI code
0040-4020(1995)51:26<7173:SOPNAH>2.0.ZU;2-M
Abstract
The preparation of six-membered N,O-heterocyclic 2H-1,3-oxazines 1 and 2H-1,3-benzoxazines 2 and the use of them in the synthesis of the cor responding alpha-amino acids 3a-c, 4a-c and oligopeptides 3d,e, 4d-f a re described These compounds are prepared based on the Ugi four-compon ent-condensation reaction.