SHIGA TOXIN-ASSOCIATED HEMOLYTIC-UREMIC SYNDROME - EFFECT OF SODIUM-BUTYRATE ON SENSITIVITY OF HUMAN UMBILICAL VEIN ENDOTHELIAL-CELLS TO SHIGA TOXIN

Authors
LOUISE CB KAYE SA BOYD B LINGWOOD CA OBRIG TG
Citation
Cb. Louise et al., SHIGA TOXIN-ASSOCIATED HEMOLYTIC-UREMIC SYNDROME - EFFECT OF SODIUM-BUTYRATE ON SENSITIVITY OF HUMAN UMBILICAL VEIN ENDOTHELIAL-CELLS TO SHIGA TOXIN, Infection and immunity, 63(7), 1995, pp. 2766-2769
Citations number
32
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
63
Issue
7
Year of publication
1995
Pages
2766 - 2769
Database
ISI
SICI code
0019-9567(1995)63:7<2766:STHS-E>2.0.ZU;2-X
Abstract
Escherichia coil O157:H7-related vascular damage such as hemolytic ure mic syndrome is believed to require the Shiga-like toxins. This study demonstrated that sodium butyrate sensitized human umbilical vein endo thelial cells to Shiga toxin and increased the expression of Shiga to xin receptor, globotriaosylceramide (Gb(3)), on human umbilical vein e ndothelial cells.