BAFILOMYCINS AND CONCANAMYCINS AS INHIBITORS OF V-ATPASES AND P-ATPASES

Authors
DROSE S ALTENDORF K
Citation
S. Drose et K. Altendorf, BAFILOMYCINS AND CONCANAMYCINS AS INHIBITORS OF V-ATPASES AND P-ATPASES, Journal of Experimental Biology, 200(1), 1997, pp. 1-8
Citations number
67
Categorie Soggetti
Biology
Journal title
Journal of Experimental Biology → ACNP
ISSN journal
00220949
Volume
200
Issue
1
Year of publication
1997
Pages
1 - 8
Database
ISI
SICI code
0022-0949(1997)200:1<1:BACAIO>2.0.ZU;2-0
Abstract
Bafilomycins and concanamycins, two groups of the plecomacrolide-defin ed class of macrolide antibiotics, have recently been recognized as im portant tools for studying the physiological role of vacuolar-type, pr oton-translocating ATPases (V-ATPases) and ATPases with phosphorylated states (P-ATPases) in animal and plant cells as well as in yeast, fun gi and bacteria. The following review will give an account of the clas sification and function of these antibiotics.