Ml. Murphy et al., ECHOGRAPHIC PSEUDOEXTENSION OF UVEAL MELANOMAS, Graefe's archive for clinical and experimental ophthalmology, 233(7), 1995, pp. 399-406
Background: Standardized echography is routinely utilized to assess uv
eal melanomas. Echographic pseudoextension is defined as normal struct
ures mimicking intrascleral or extrascleral extension of tumor on echo
graphy. Methods: The records of 151 consecutive uveal melanoma patient
s evaluated with standardized echography over a 6-year period (1986-19
91) were reviewed to identify those in which pseudoextension or true e
xtension was diagnosed. Results: Fourteen (9%) cases of pseudoextensio
n were noted, with causes including juxtapapillary tumor location (sev
en cases), extraocular muscle insertion (five cases), vortex ampullae
(one case), and post-brachytherapy changes (one case). Clinical, echog
raphic, and/or histopathologic follow-up confirmed absence of true ext
ension. Six (4%) cases of true extrascleral extension were identified
and confirmed histopathologically. Conclusion: Differentiating extraoc
ular tumor extension from pseudoextension is critical, and use of stan
dardized A-scan and contact B-scan echography is integral in this asse
ssment.