OBJECTIVE-To determine the prevalence of pregnancy complicated by diab
etes in a representative sample of the U.S. population. RESEARCH DESIG
N AND METHODS-We analyzed data from a multistaged cross-sectional prob
ability sample of live births recorded in the U.S. in 1988 for women 1
5-49 years of age. The main outcome measure was pregnancy complicated
by diabetes. RESULTS-Diabetes was present in similar to 154,000 (4%) o
f all pregnancies in the U.S. Gestational diabetes mellitus (GDM) acco
unted for 135,000 of such pregnancies (88%), non-insulin-dependent dia
betes mellitus (NIDDM) for 12,000 (8%), and insulin-dependent diabetes
mellitus for 7,000 (4%). On average, the mothers with NIDDM (29.6 yea
rs) and GDM (29.3 years) were older than mothers whose pregnancies wer
e not complicated by diabetes (26.2 years; P < 0.05). In multivariate
analyses, the odds of having a pregnancy complicated by GDM increased
significantly with maternal age and body mass index. CONCLUSIONS-Pregn
ancy is complicated by diabetes more often than was previously believe
d. More frequent testing may further increase the apparent prevalence
of GDM.