PURIFICATION AND CDNA SEQUENCE OF A MURINE PROTEIN HOMOLOGOUS TO THE HUMAN P62 TYROSINE PHOSPHOPROTEIN THAT ASSOCIATES WITH THE RAS GTPASE-ACTIVATING PROTEIN P120 GAP

Authors
AGGER R FREIMUTH P
Citation
R. Agger et P. Freimuth, PURIFICATION AND CDNA SEQUENCE OF A MURINE PROTEIN HOMOLOGOUS TO THE HUMAN P62 TYROSINE PHOSPHOPROTEIN THAT ASSOCIATES WITH THE RAS GTPASE-ACTIVATING PROTEIN P120 GAP, Gene, 158(2), 1995, pp. 307-308
Citations number
7
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
158
Issue
2
Year of publication
1995
Pages
307 - 308
Database
ISI
SICI code
0378-1119(1995)158:2<307:PACSOA>2.0.ZU;2-E
Abstract
A 68-kDa protein that binds to the murine dendritic cell-specific mono clonal antibody M342 was purified and its amino acid sequence was part ially determined. Corresponding cDNA clones code for a protein that is closely related to a 62-kDa human protein (p62) that associates with the Ras GTPase-activating protein, p120 GAP, suggesting that p62 may h ave a dendritic cell-specific function or that an M342 cross-reactive epitope may exist on the murine p62 molecule.