A TSP509I VARIANT IN EXON-13 OF THE NEUROFIBROMATOSIS TYPE-1 (NF1) GENE ALLOWS THE IDENTIFICATION OF BOTH ALLELES AT THE MESSENGER-RNA LEVEL

Authors
REGNIER V DANGLOT G NGUYEN VG BERNHEIM A
Citation
V. Regnier et al., A TSP509I VARIANT IN EXON-13 OF THE NEUROFIBROMATOSIS TYPE-1 (NF1) GENE ALLOWS THE IDENTIFICATION OF BOTH ALLELES AT THE MESSENGER-RNA LEVEL, Human genetics, 96(1), 1995, pp. 131-132
Citations number
7
Categorie Soggetti
Genetics & Heredity
Journal title
Human genetics → ACNP
ISSN journal
03406717
Volume
96
Issue
1
Year of publication
1995
Pages
131 - 132
Database
ISI
SICI code
0340-6717(1995)96:1<131:ATVIEO>2.0.ZU;2-M
Abstract
We describe here a new sequence variant occurring in the coding region of the neurofibromatosis (NF1) gene (exon 13). This exonic polymorphi sm can be directly investigated by simple restriction enzyme digestion of RT-PCR (reverse transcription-polymerase chain reaction) products, making it a powerful tool for examining allele-specific mRNA expressi on levels.