PCR-MEDIATED GENETIC TYPING OF PATHOGENIC MICROORGANISMS

Basic principles, characteristics, methodical peculiarities, and strat egy of choice of PCR-mediated methods of genetic typing are discussed. Existing and potential fields of application of these methods for tac kling many unsolved problems of molecular epidemiology of bacterial in fections are considered. Advantages of PCR-mediated methods of genetic typing compared with other techniques used for studying genomic polym orphism are demonstrated, Possibilities for developing novel PCR-media ted methods with the aim of improving genetic typing are analyzed.