FIRST SYNTHESIS OF SECONDARY P-ALKENYL AND P-ALKYNYL PHOSPHINE OXIDES

A general method for preparing secondary P-alkenyl and P-alkynyl phosp hine oxides, compounds unknown so far, involves the condensation of th e vinyl Grignard reagent or lithium acetylide on P-chloroaminophosphin es followed by acidic hydrolysis of the corresponding vinyl- or ethyny laminophosphines on a solid acid (Amberlyst 15). The few reported chem ical properties are mainly related to the strong PH bond activation. O f special interest is the addition of a secondary vinylphosphine oxyde derivative on methyl acrylate which occurs at room temperature withou t any catalyst.