NEW SYNTHESIS OF THE CYCLIC TETRAPEPTIDE TENTOXIN EMPLOYING AN AZLACTONE AS KEY INTERMEDIATE

Authors
CAVELIER F VERDUCCI J
Citation
F. Cavelier et J. Verducci, NEW SYNTHESIS OF THE CYCLIC TETRAPEPTIDE TENTOXIN EMPLOYING AN AZLACTONE AS KEY INTERMEDIATE, Tetrahedron letters, 36(25), 1995, pp. 4425-4428
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
25
Year of publication
1995
Pages
4425 - 4428
Database
ISI
SICI code
0040-4039(1995)36:25<4425:NSOTCT>2.0.ZU;2-8
Abstract
An improved preparation of the cyclic tetrapeptide Tentoxin is reporte d employing an azlactone as key intermediate. This new synthetic route offers the advantage over existing methodologies that the dehydro ami no acid would easily be varied, thus allowing the simple preparation o f analogues.