HIGHLY CONVENIENT ROUTE TO OPTICALLY PURE ALPHA-AMINOPHOSPHONIC ACIDS

Citation
R. Hamilton et al., HIGHLY CONVENIENT ROUTE TO OPTICALLY PURE ALPHA-AMINOPHOSPHONIC ACIDS, Tetrahedron letters, 36(25), 1995, pp. 4451-4454
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
36
Issue
25
Year of publication
1995
Pages
4451 - 4454
Database
ISI
SICI code
0040-4039(1995)36:25<4451:HCRTOP>2.0.ZU;2-H
Abstract
Pure diasteriomers, obtained simply and directly by reaction of hypoph osphorous acid salts of (R)(+) or (S)(-) - N-alpha-methylbenzylamine w ith aldehydes, can be simultaneously deprotected and oxidised in one s tep to provide a highly convenient synthesis of a aminophosphonic acid s in high optical purity.