Lb. Ellwein et Mf. Drummond, ECONOMIC-ANALYSIS ALONGSIDE CLINICAL-TRIALS - BIAS IN THE ASSESSMENT OF ECONOMIC OUTCOMES, International journal of technology assessment in health care, 12(4), 1996, pp. 691-697
Clinical trial randomization schemes to control patient characteristic
s that can influence clinical response are not sufficient to control f
or their effects on operational efficiency and cost within the provide
r institution. This variation can result in biased economic findings w
hen patients are allowed to select a provider themselves.