The aorta is the most frequent site for atherosclerosis, and is more f
requent than the internal carotids or cerebral arteries. Transesophage
al echocardiography has made it possible to identify atheromatous lesi
ons of the aortic arch which are situated before the branches to the n
eck vessels and are capable of causing embolic cerebral events. These
atheromatous plaques can be irregular, may protrude into the aortic lu
men and sometimes have loose thrombus attached to them. The risk of st
rokes and transient ischemic attacks appears to be higher when plaques
are more than 4 mm in thickness and when mobile components are presen
t. Atheroma in the ascending aorta and aortic arch is a significant ri
sk factor for cerebral ischemia, independent of high-grade carotid ste
nosis. Aortic atherosclerotic lesions should particulary be looked for
in patients with a history of repeated peripheral and cerebral emboli
sm, in whom no obvious embolic cause is found. A standard protocol for
treatment of these potentially embolic aortic lesions has not get bee
n agreed upon, but the use of antiplatelet drugs or vitamin-K antagoni
sts treatment should be considered.