CANINE IMMUNE-MEDIATED DIABETES-MELLITUS - A CASE-REPORT

A four-year-old, spayed female toy fox ferrier presented with hypergly cemia and severe anemia. A diagnosis of immune-mediated diabetes melli tus was made based upon the finding of beta-cell specific antibodies. immune-mediated hemolytic anemia was diagnosed based on findings of a regenerative anemia, spherocytosis, hyperbilirubinemia, hemoglobinuria , and bilirubinuria. The anemia resolved following two months of immun osuppressive therapy. The diabetes was treated with insulin for four m onths, after which time treatment was no longer necessary. However, th e dog remained positive for beta-cell antibodies which may be a predic tive marker for the recurrence of diabetes mellitus in the future.