L. Langlaisburgess et al., CONCURRENT HYPOADRENOCORTICISM AND HYPOALBUMINEMIA IN DOGS - A RETROSPECTIVE STUDY, The Journal of the American Animal Hospital Association, 31(4), 1995, pp. 307-311
A retrospective study was undertaken to determine the prevalence of hy
poalbuminemia in dogs with hypoadrenocorticism. During a 94-month inte
rval, 17 of 44 dogs (38.6%) with hypoadrenocorticism were found to hav
e hypoalbuminemia. When compared to all dogs with hypoalbuminemia (9.8
%) observed in the hospital population during this same interval, ther
e appeared to be a significant association between canine adrenocortic
al insufficiency and hypoalbuminemia. The pathogenesis of the hypoalbu
minemia in this study is speculative; possible mechanisms include gast
rointestinal blood loss, protein-losing enteropathy, malassimilation,
or decreased albumin synthesis. Renal protein loss was not supported b
y routine urinalysis findings.