DRUG OR TOOL, DESIGN OR SERENDIPITY

Authors
VERLINDE CLMJ DIJKSTRA BW
Citation
Clmj. Verlinde et Bw. Dijkstra, DRUG OR TOOL, DESIGN OR SERENDIPITY, Nature structural biology, 2(6), 1995, pp. 429-432
Citations number
23
Categorie Soggetti
Biology,"Cell Biology
Journal title
Nature structural biology → ACNP
ISSN journal
10728368
Volume
2
Issue
6
Year of publication
1995
Pages
429 - 432
Database
ISI
SICI code
1072-8368(1995)2:6<429:DOTDOS>2.0.ZU;2-W
Abstract
Iterative protein structure-based ligand design has led to a 'selectiv e' inhibitor of human nonpancreatic secretory phospholipase A(2) which provides a new tool for probing metabolic pathways and may lead to a useful drug.