PARTIAL MOLAR ISENTROPIC PRESSURE COEFFICIENTS OF SOME N-ACETYL AMINO-ACID AND PEPTIDE AMIDES AT INFINITE DILUTION IN AQUEOUS-SOLUTIONS AT THE TEMPERATURE 298.15 K

The partial molar isentropic pressure coefficients at infinite dilutio n k(S,2)(infinity) = -(partial derivative V-2(infinity)/partial deriva tive p)s, where V-2(infinity) is the partial molar volume at infinite dilution, have been determined for six N-acetyl amino acid and peptide amides in aqueous solution at the temperature 298.15 K. The results o btained have been rationalized in terms of the likely solute - water i nteractions. The contribution of an alanyl side-chain to the value of k(S,2)(infinity) of a peptide has been derived. The result obtained is almost in agreement with that reported in previous work. (C) 1995 Aca demic Press Limited