The sensory feedback control system plays a central role in human loco
motion. However, few studies have been published discussing the influe
nce of sensory input at the plantar surface of the foot on the kinemat
ics and kinetics of locomotion, The purpose of this study was to exami
ne the effect of changes in sensory input at the plantar surface of th
e foot on the pressure distribution measured at the plantar surface of
the foot. Three pairs of specially made socks with sand at the planta
r surface of the foot and one pair of normal socks were used to simula
te different sensory inputs. Pressure distribution at the plantar surf
ace of the foot was measured using an EMED system for 10 subjects for
each of the four sensory input conditions during walking and running o
n a treadmill. The results showed significant and substantial changes
in pressure in selected areas for changes in sensory input. The pressu
re increased in the midfoot area and decreased in the toe area with in
creasing sensory inputs. These results are similar to results of a pre
vious study where similar changes were found in a comparison between c
omfortable and uncomfortable shoes. Relevance Pressure distribution is
increasingly used in clinical assessments. However, the factors influ
encing the pressure distribution pattern are only partially understood
. One factor may be the sensory input into the foot. It is important t
o understand this influence in order to provide appropriate interpreta
tion of the pressure distribution data.