V. Tanner et al., AUTOMATED ACHROMATIC CONTRAST AND CHROMATIC DISCRIMINATION SENSITIVITY TESTING IN DYSTHYROID OPTIC NEUROPATHY, Eye, 9, 1995, pp. 352-357
Our experience of patients with dysthyroid eye disease shows that norm
al chromatic discrimination sensitivity precludes the diagnosis of opt
ic nerve compression (31 patients), and that clinically confirmed opti
c nerve compression is invariably associated with decreased chromatic
discrimination sensitivity thresholds (8 patients), Dysthyroid patient
s enrolled in this study underwent automated achromatic contrast and c
hromatic discrimination sensitivity testing on presentation, with repe
at assessment of those patients suspected of developing optic nerve co
mpression, If chromatic discrimination sensitivity was decreased, pati
ents were followed up more frequently. If abnormal chromatic discrimin
ation sensitivity was accompanied by a relative afferent pupillary def
ect (RAPD) or decreased Snellen visual activity (VA), then optic nerve
decompression was performed, The automated chromatic discrimination s
ensitivity test described represents a quick, reproducible and cheap c
linical test which we feel is of value in assessing patients with dyst
hroid eye disease, We suggest that sequential chromatic discrimination
sensitivity assessment is a sensitive and effective way of monitoring
patients at risk of dysthyroid optic neuropathy.