A strain of cytopathic virus, named strain TG/K79, was isolated from t
he brain of a newborn piglet, pure Hampshire breed, which died shortly
after birth. The physicochemical property of virus was considered to
be that of the family Adenoviridae. A significant difference between o
ur isolate and 4 reference porcine adenoviruses was demonstrated by cr
oss-seroneutralization test. Differences between TG/K79 and other porc
ine adenoviruses were also seen in electrophoretic patterns of viral D
NA in agarose gel after digested by restiction endonucleases. Two SPF
pigs, 2-month-old, experimentally infected via intranasal showed a fev
er and a hemorrhagic enteritis. A serological survey indicates that at
least swine in the farm where the virus was isolated have been highly
contaminated.