Heart rate variability (HRV) is a measure of autonomic nervous system
balance/imbalance. Measurement and analysis of HRV can be classified i
nto time domain analysis and frequency domain analysis. Time domain an
alysis is a general measure of autonomic nervous system balance and is
based on altered versions of the measurement of the standard deviatio
n of heart period, defined in terms of the sinus R-R intervals over ti
me. There are six commonly used time domain measurements: SDANN, 24-hr
SD, SD, RMSSD, RR50, and % RR50. Frequency domain analysis uses eithe
r autoregressive or fast Fourier transform techniques to delineate par
asympathetic (high-frequency components) from sympathetic (low-frequen
cy components) of autonomic control. This study explores the clinical
applications of HRV with respect to respiratory sinus arrhythmia, exer
cise, mortality, sudden cardiac arrest, myocardial infarction, and con
gestive heart failure.