The most frequently occurring and important cause of gastric outlet ob
struction in the neonate and young infant is infantile hypertrophic py
loric stenosis (IHPS). A reported association of IHPS and eosinophilic
gastroenteritis [1] raises interesting questions about the possible e
tiologic relationship between the two entities. It is plausible that t
he observed sonographic pyloric muscular wall thickness in IHPS may in
part be dependent on the degree and duration of an allergic gastroent
eropathy. A recent report suggests that endoscopy may be a more reliab
le diagnostic method than sonography in the patient with evolving IHPS
[2]. Our recent experience with a patient with evolving IHPS supports
the findings described in these prior reports.