SUPEROVULATION INDUCTION BY HUMAN MENOPAUSAL GONADOTROPIN IN RABBITS

Superovulation induction in laboratory animals is an important techniq ue as a means of providing eggs for embryonic research. Superovulation induction by human menopausal gonadotrophin (HMG) has not been fully established in rabbits. In the present. study, the relationship betwee n the dosage of injected HMG and the superovulatory response including fertilization rate was studied. The most satisfactory result was obta ined in the group in which 30 iu of HMG was injected subcutaneously th ree times at 24-hr intervals. The superovulatory response by this meth od was considerably better than that by conventional six injections of follicle-stimulating hormone (FSH) having been widely accepted.