THE DNA-SEQUENCE OF A 7941-BP FRAGMENT OF THE LEFT ARM OF CHROMOSOME-VII OF SACCHAROMYCES-CEREVISIAE CONTAINS 4 OPEN READING FRAMES INCLUDING THE MULTICOPY SUPPRESSOR GENE OF THE POP2 MUTATION AND A PUTATIVE SERINE THREONINE PROTEIN-KINASE GENE

We report the sequence of a 7941 bp DNA fragment from the left arm of chromosome VII of Saccharomyces cerevisiae which contains four open re ading frames (ORFs) of greater than 100 amino acid residues. ORF biC83 4 shows 100% bp identity with the recently identified multicopy suppre ssor gene of the pop2 mutation (MPT5); its deduced protein product car ries an eight-repeat domain region, homologous to that found in the hy pothetical regulatory YGL023 protein of S. cerevisiae and the Pumilio protein of Drosophila. ORF biE560 protein exhibits patterns typical of serine/threonine protein kinases, with which it shares high degrees o f homology. The complete nucleotide sequence was submitted to the EMBL Data Library under Accession Number X83690.