AN UNWANTED SIDE-EFFECT OF HYDROXYUREA IN A PATIENT WITH IDIOPATHIC MYELOFIBROSIS

Authors
STARMANSKOOL MJF FICKERS MMF PANNEBAKKER MAG
Citation
Mjf. Starmanskool et al., AN UNWANTED SIDE-EFFECT OF HYDROXYUREA IN A PATIENT WITH IDIOPATHIC MYELOFIBROSIS, Annals of hematology, 70(5), 1995, pp. 279-280
Citations number
15
Categorie Soggetti
Hematology
Journal title
Annals of hematology → ACNP
ISSN journal
09395555
Volume
70
Issue
5
Year of publication
1995
Pages
279 - 280
Database
ISI
SICI code
0939-5555(1995)70:5<279:AUSOHI>2.0.ZU;2-V
Abstract
A patient with idiopathic myelofibrosis is reported who developed a dr ug fever after treatment with hydroxyurea, a generally effective and w ell-tolerated drug in chronic myeloproliferative syndromes. Typically, this form of fever develops after a few weeks of exposure to the drug and disappears with discontinuation of the drug. Possible interaction s with prostaglandin or leukotriene metabolism may play a role.