This article explores methodological and ethical issues in the conduct
of research with vulnerable families. Some methodological and ethical
issues are common to all family research, regardless of the families'
vulnerability; however, many research issues are more problematic in
vulnerable families, and a few issues are relatively unique to vulnera
ble families. Vulnerable families are defined as families that are sus
ceptible to harm because of their socioeconomic status, their minority
status, or other stigmatizing status. Methodological issues include d
efinition of family; recruitment and retention of participants; reliab
ility and validity of instruments; and racism, classism, and sexism. E
thical issues include confidentiality, reporting abuse and neglect, co
nflict of research ethics and personal ethics, identifying problems no
body can fix, balancing demands and benefits, and interpretation of da
ta. Examples of methodological and ethical issues are drawn from sever
al research studies in which the primary author was or is currently in
volved.