Sdh. Malnick et al., HCV HEPATITIS ASSOCIATED WITH ANTICARDIOLIPIN ANTIBODY AND A CEREBROVASCULAR ACCIDENT - RESPONSE TO INTERFERON THERAPY, Journal of clinical gastroenterology, 24(1), 1997, pp. 40-42
A 54-year-old man with chronic hepatitis C virus (HCV) developed quadr
ihemianopsia caused by lacunar brain infarction. Extensive evaluation
revealed high titers of anticardiolipin antibodies (ACA). Following in
terferon treatment (6 x 10(6), three times a week for 2 months and 3 x
10(6) for another 7 months), liver transaminase levels decreased to n
ormal, HCV RNA in blood was no longer detectable, concomitantly with t
he disappearance of the ACA. The patient remained clinically stable wi
thout evidence for either HCV activity (RNA) or ACA or further thrombo
embolic events.