ANTIFUNGAL COPYRINE ALKALOIDS - CRYSTAL-STRUCTURE OF 3-METHYLSAMPANGINE

Authors
PETERSON JR ZJAWIONY JK CLARK AM HUFFORD CD ROGERS RD
Citation
Jr. Peterson et al., ANTIFUNGAL COPYRINE ALKALOIDS - CRYSTAL-STRUCTURE OF 3-METHYLSAMPANGINE, Journal of chemical crystallography, 25(5), 1995, pp. 223-226
Citations number
9
Categorie Soggetti
Crystallography,Spectroscopy
Journal title
Journal of chemical crystallography → ACNP
ISSN journal
10741542
Volume
25
Issue
5
Year of publication
1995
Pages
223 - 226
Database
ISI
SICI code
1074-1542(1995)25:5<223:ACA-CO>2.0.ZU;2-T
Abstract
3-Methylsampangine, C16H10N2O, crystallizes in the monoclinic space gr oup P2(1)/c with a = 7.260(3), b = 10.697(5), c = 15.342(6) Angstrom, and beta = 102.69(4). All nonhydrogen atoms of this potent antifungal agent are planar to within 0.082 Angstrom. The title compound exhibits potent in vitro antifungal activity against C. neoformans, C. albican s and A. fumigatus.