SUBCUTANEOUS, OMENTUM AND TUMOR FATTY-ACID COMPOSITION, AND SERUM-INSULIN STATUS IN PATIENTS WITH BENIGN OR CANCEROUS OVARIAN OR ENDOMETRIAL TUMORS - DO TUMORS PREFERENTIALLY UTILIZE POLYUNSATURATED FATTY-ACIDS

Authors
YAM D BENHUR H DGANI R FINK A SHANI A BERRY EM
Citation
D. Yam et al., SUBCUTANEOUS, OMENTUM AND TUMOR FATTY-ACID COMPOSITION, AND SERUM-INSULIN STATUS IN PATIENTS WITH BENIGN OR CANCEROUS OVARIAN OR ENDOMETRIAL TUMORS - DO TUMORS PREFERENTIALLY UTILIZE POLYUNSATURATED FATTY-ACIDS, Cancer letters, 111(1-2), 1997, pp. 179-185
Citations number
44
Categorie Soggetti
Oncology
Journal title
Cancer letters → ACNP
ISSN journal
03043835
Volume
111
Issue
1-2
Year of publication
1997
Pages
179 - 185
Database
ISI
SICI code
0304-3835(1997)111:1-2<179:SOATFC>2.0.ZU;2-I
Abstract
The relationships between the fatty acid composition of cancerous endo metrium and ovary, and peripheral adipose tissues were studied in Isra eli Jewish women, and are presented together since no differences were shown between them. The results suggest a mobilization of linoleic ac id from subcutaneous and omental depots and its incorporation into tum ors accompanied by a high degree of desaturation. High blood insulin c oncentrations characterized patients with stage I and II disease, and low concentrations characterized patients with advanced degrees of mal ignancy. (C) 1997 Elsevier Science Ireland Ltd.