Kh. Baek et Wp. Hanratty, THE LETHAL (2)GIANT LARVA (L(2)GL), A RECESSIVE ONCOGENE, IS REQUIREDDURING EMBRYONIC AND POSTEMBRYONIC DEVELOPMENT IN DROSOPHILA, Cancer letters, 111(1-2), 1997, pp. 233-238
Recessive oncogenes have genetic functions important for the regulatio
n of tissue growth and differentiation. Defining the role of these gen
es in normal developmental and physiological processes is important to
the development of the accurate models of the normal regulation of gr
owth and differentiation: We report here a genetic analysis of the req
uirement for the lethal (2) giant larva function during development. T
he results demonstrate that the lethal (2) giant larva function is req
uired during embryonic and post-embryonic development to maintain the
normal developmental capacity. (C) 1997 Elsevier Science Ireland Ltd.