T. Wijtzes et al., MODELING BACTERIAL-GROWTH OF LACTOBACILLUS-CURVATUS AS A FUNCTION OF ACIDITY AND TEMPERATURE, Applied and environmental microbiology, 61(7), 1995, pp. 2533-2539
Models that describe the effect of acidity, temperature, and the combi
ned effect of these variables on the growth parameters of Lactobacillu
s curvatus are developed and validated. Growth parameters (lag time, s
pecific growth fate, and maximum population density) were calculated f
rom growth data at different temperature-acidity combinations. Experim
ents were set up to assess the quantitative effects of temperature and
acidity on the growth parameters rather than for parameter estimation
solely. The effect of acidity is monitored at several constant temper
ature values. Models are set up and fitted to the. data. The same proc
edure is used at constant acidity values to model the effect of temper
ature. For lag time, specific growth rate, and maximum population dens
ity, the effect of temperature could be multiplied with the effect of
acidity tb obtain combinatory models that describe the effect of both
controlling factors on the growth parameters. Lag time measurements sh
owed large deviations, and therefore the lag time models developed can
only. be used to estimate the order of magnitude of lag time.