STUDY OF THE XENOBIOPROSTHETIC VALVES BY THE EPR TECHNIQUE

Copper (II) ions were used as paramagnetic labels to study the role of functional groups of structural proteins (SP) of xenobioprosthetic va lves in the process of transition metal ions coordination as well as f or investigation of changes in complexing properties of these proteins under influence of the recipient media. The dependence of Cu(II) coor dination sphere composition in complexes with SP on the pH-value has b een determined. Research of influence of the valves' calcification pro cess on the coordination properties of the SP are in progress.