INDUCTION OF AN INTERLEUKIN-1 RECEPTOR ANTAGONIST-LIKE COMPONENT PRODUCED FROM MOUSE SPLEEN-CELLS BY BOVINE KAPPA-CASEINOGLYCOPEPTIDE

Authors
OTANI H MONNAI M
Citation
H. Otani et M. Monnai, INDUCTION OF AN INTERLEUKIN-1 RECEPTOR ANTAGONIST-LIKE COMPONENT PRODUCED FROM MOUSE SPLEEN-CELLS BY BOVINE KAPPA-CASEINOGLYCOPEPTIDE, Bioscience, biotechnology, and biochemistry, 59(6), 1995, pp. 1166-1168
Citations number
25
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
59
Issue
6
Year of publication
1995
Pages
1166 - 1168
Database
ISI
SICI code
0916-8451(1995)59:6<1166:IOAIRA>2.0.ZU;2-H
Abstract
Bovine kappa-caseinoglycopeptide (residues 106-169, CGP) bound to mous e plastic-adherent cells. A culture supernatant prepared from mouse sp leen cells and plastic-adherent cells cultured with CGP significantly inhibited the lipopolysaccharide-induced proliferative response of mou se spleen lymphocytes. The inhibition of proliferation by the culture supernatant was completely overcome by the addition of the anti-interl eukin-l receptor antagonist antibody.