HEPATOPROTECTION BY PHYLLANTHUS-AMARUS AND PHYLLANTHUS-DEBILIS IN CCL4-INDUCED LIVER DYSFUNCTION

The present investigation compares the hepatoprotective action of Phyl lanthus amarus and Phyllanthus debilis in the treatment of liver damag e in rats exposed to carbon tetrachloride. The evaluation has been car ried out using liver function marker enzymes in plasma, liver tissue b iochemistry supported by liver histopathology. The extent of recovery has been compared with the natural liver regeneration after CCl4 damag e. Both the plant species have been found to be effective in the treat ment of liver damage induced by CCl4. P. debilis has been found to be a better hepatoprotective agent than P. amarus.